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LS-DYNA modeling helps develop engineered cartilage

The Annals of Biomedical Engineering has published “The effect of moving point of contact stimulation on chondrocyte gene expression and localization in tissue engineered constructs.” , a paper by Jake Kaupp. Markus Hetzler and our Thumbprint Solutions team contributed advanced numerical modeling to help understand the behaviour of seeded agarose gel under cyclic loading.  This viscoelastic material is extremely complex, and we successfully developed and applied material model development techniques using numerical optimization to create and validate the material models.  Ultimately this work will help develop new materials for joints.

Agarose Strain

Strain history in cyclic loading of agarose gel

Thumbprint Solutions has been proudly supporting biomechanics research at Queens University and the Human Mobility Research Centre by supplying advanced simulation technology and custom test equipment development. Helping patient outcomes through core engineering.

Find the paper here:

The effect of moving point of contact stimulation on chondrocyte gene expression and localization in tissue engineered constructs.

 

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